Telomeres are structures at the ends of chromosomes, and in normal cells, they shorten each time the cell divides. This is called “cellular aging.” When telomeres shorten to a certain extent, cells are no longer able to divide, and normal cells die. By killing them, they prevent cells from multiplying abnormally and becoming cancerous in the body. On the other hand, cells that survive without dying are called “senescent cells,” and it has been discovered that the substance SASP (secretory trait associated with cell senescence) produced by these cells causes cancerous transformation of surrounding cells. When cells become cancerous, they begin to use an enzyme called telomerase to lengthen telomeres to maintain cell division. It is thought that telomerase is already expressed at the stage of so-called precancerous lesions before cells become cancerous, and by examining the messenger RNA of telomerase, it is possible to predict the early stages of cancerous transformation. The TAQ test detects this messenger RNA. TAQ test is an acronym for “Telomerase-Activity-Quantification,” which means “a test that measures the activity of telomerase.” This test can only be performed in Japan, which currently has the world’s highest level of patented technology for measuring messenger RNA. In conventional medicine, measuring the amount of proteins such as enzymes and tumor markers has been used as a guide to the health of the body and diseases such as cancer. However, in the human body, messenger RNA, which acts as a command to make proteins, can be used to understand pathological conditions occurring in the body earlier than finished proteins. Telomerase is an enzyme that synthesizes telomeres, and it has been found that more than 90% of cancers use it for proliferation, so it can be used for early detection of cancer. When you hear the phrase “an enzyme that lengthens telomeres,” you may think that having a large amount of telomerase is good for your body, but in reality, the opposite is true; when a large amount of telomerase is expressed, it suggests a risk of becoming prone to cancer.
Using this testing method, it is possible to detect diseases other than cancer early and confirm the effectiveness of disease treatment.
You will be able to do this. In addition, by continuously measuring messenger RNA,
You can manage your health condition. Furthermore, by converting immune-related RNA into data, it is possible to closely manage the health status of an individual.
Diseases that can be detected early
Brain disease/mental illness
By examining the precursor states of diseases that are thought to be caused by the activation/inactivation of abnormal proteins and neurotransmitters, the possibility of early detection and treatment increases.
(Alzheimer’s disease, senile dementia, developmental disorders, depression, etc.)
Cancer/Tumor (neoplasm)
Tumors, whether benign or malignant, actively synthesize proteins (tumor markers), so by testing the messenger RNA activity of tumor-specific tumor markers, it is possible to diagnose a specific cancer at an early stage or to diagnose recurrence after treatment.
Diseases caused by endocrine abnormalities
Diseases caused by the abundance of substances biosynthesized using mRNA as a template, such as peptide hormones, and enzymes whose main components are proteins, are subject to early detection.
(Many internal organs diseases, diabetes, Graves’ disease, gout, etc.)
The activity level of immune cells themselves can be detected in advance. It is also possible to check for poor lifestyle habits that lead to weakened immunity. (autoimmune diseases, reactions to allergies, tumor immunity status, etc.)
